Citalopram is an SSRI used for depression and anxiety disorders. It is the SSRI with the lowest interaction profile.
Also known as: citalopram, celexa
Most selective SSRI. Lowest interaction profile among SSRIs.
Selective serotonin reuptake inhibition (SERT). Low affinity for other transporters and receptors.
Complete oral absorption. Bioavailability: 80%. Peak: 1-4 h.
Metabolised by CYP2C19 and CYP3A4. Less CYP2D6 dependent than other SSRIs.
35 h.
No documented drug–drug interactions for this medicine.
Alcohol potentiates sedation; with QT prolongation, heavy drinking adds cardiac risk.
Moderate alcohol; extra caution with QT risk factors.
EMC-UK — Citalopram SmPC 4.5/4.7 (alcohol, QT).
No documented disease interactions.
No documented pregnancy or breastfeeding information.
Clinical and educational support tool. The information does not replace a medical prescription or the opinion of a qualified healthcare professional.
Medicines from the same therapeutic group (ATC classification) or the same pharmacological class.
